The Current Opinion journals were developed out of the recognition that it is increasingly difficult for specialists to keep up to date with the expanding volume of information published in their subject. Elsevier’s Current Opinion journals comprise of 26 leading titles in life sciences and adjacent fields.

Current Opinion in Systems Biology

Issues per year: 6 issues
Editorial Board

Current Opinion in Systems Biology

Current Opinion in Systems Biology is a new systematic review journal that aims to provide specialists with a unique and educational platform to keep up-to-date with the expanding volume of information published in the field of Systems Biology. It publishes polished, concise and timely systematic reviews and opinion articles. In addition to describing recent trends, the authors are encouraged to give their subjective opinion on the topics discussed. As this is such a broad discipline, we have determined themed sections each of which is reviewed once a year.

The following 12 areas will be covered by Current Opinion in Systems Biology:

  • Genomics and Epigenomics
  • Gene Regulation
  • Metabolic Networks
  • Cancer and Systemic Diseases
  • Mathematical Modelling
  • Big Data Acquisition and Analysis
  • Systems Pharmacology and Physiology
  • Synthetic Biology
  • Stem Cells, Development, and Differentiation
  • Systems Biology of Mold Organisms
  • Systems Immunology and Host-Pathogen Interaction
  • Systems Ecology and Evolution

Section Editors, who are major authorities in the field, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasized. Section Editors commission reviews from authorities on each topic that they have selected.

Reviews

Authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous year.

Editorial Overview

Section Editors write a short overview at the beginning of the section to introduce the reviews and to draw the reader's attention to any particular interesting developments.

Invited authors are encouraged to visit our Guide for Authors for information on article submission.

Best Cited over the last year.

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An operational view of intercellular signaling pathways

Volume 1, Issue , 01 February 2017, Pp 16-24
Yaron E. Antebi | Nagarajan Nandagopal | Michael B. Elowitz

Current state and applications of microbial genome-scale metabolic models

Volume 2, Issue , 01 April 2017, Pp 10-18
Won Jun Kim | Hyun Uk Kim | Sang Yup Lee

System-level understanding of plant mineral nutrition in the big data era

Volume 4, Issue , 01 August 2017, Pp 71-77
Hatem Rouached | Seung Y. Rhee

Repertoire sequencing and the statistical ensemble approach to adaptive immunity

Volume 1, Issue , 01 February 2017, Pp 44-47
Curtis G. Callan | Thierry Mora | Aleksandra M. Walczak

Recent developments in models of calcium signalling

Volume 3, Issue , 01 June 2017, Pp 15-22
Geneviève Dupont | James Sneyd

Ecological systems biology: The dynamics of interacting populations

Volume 1, Issue , 01 February 2017, Pp 114-121
Jonathan Friedman | Jeff Gore

Current status of mathematical modeling of cancer - from the viewpoint of cancer hallmarks

Volume 2, Issue , 01 April 2017, Pp 39-48
Shigeyuki Magi | Kazunari Iwamoto | Mariko Okada-Hatakeyama

Quantitative systems pharmacology and the personalized drug-microbiota-diet axis

Volume 4, Issue , 01 August 2017, Pp 43-52
Ines Thiele | Catherine M. Clancy | Almut Heinken | Ronan M.T. Fleming

Unlocking the potential of plant phenotyping data through integration and data-driven approaches

Volume 4, Issue , 01 August 2017, Pp 58-63
Frederik Coppens | Nathalie Wuyts | Dirk Inzé | Stijn Dhondt

Mechanisms of cell polarization

Volume 3, Issue , 01 June 2017, Pp 43-53
Wouter Jan Rappel | Leah Edelstein-Keshet

Single cells make big data: New challenges and opportunities in transcriptomics

Volume 4, Issue , 01 August 2017, Pp 85-91
Philipp Angerer | Lukas Simon | Sophie Tritschler | F. Alexander Wolf | David Fischer | Fabian J. Theis

Advances and applications of immune receptor sequencing in systems immunology

Volume 1, Issue , 01 February 2017, Pp 62-68
Paul Lindau | Harlan S. Robins

Computational systems biology of epithelial-hybrid-mesenchymal transitions

Volume 3, Issue , 01 June 2017, Pp 1-6
Mohit Kumar Jolly | Herbert Levine

Engineering protein glycosylation in prokaryotes

Volume 5, Issue , 01 October 2017, Pp 23-31
Timothy G. Keys | Markus Aebi

Dissecting chromatin-mediated gene regulation and epigenetic memory through mathematical modelling

Volume 3, Issue , 01 June 2017, Pp 7-14
Leonie Ringrose | Martin Howard

Genome variation across cancers scales with tissue stiffness - An invasion-mutation mechanism and implications for immune cell infiltration

Volume 2, Issue , 01 April 2017, Pp 103-114
Charlotte R. Pfeifer | Cory M. Alvey | Jerome Irianto | Dennis E. Discher

Non-coding genetic variation in cancer

Volume 1, Issue , 01 February 2017, Pp 9-15
Tawny N. Cuykendall | Mark A. Rubin | Ekta Khurana

Cancer systems biology: Live imaging of intestinal tissue in health and disease

Volume 2, Issue , 01 April 2017, Pp 19-28
Bas Ponsioen | Hugo J. Snippert

Interactome-based approaches to human disease

Volume 3, Issue , 01 June 2017, Pp 88-94
Michael Caldera | Pisanu Buphamalai | Felix Müller | Jörg Menche

Chemical genetics in drug discovery

Volume 4, Issue , 01 August 2017, Pp 35-42
Elisabetta Cacace | George Kritikos | Athanasios Typas

Stem cell self-renewal in regeneration and cancer: Insights from mathematical modeling

Volume 5, Issue , 01 October 2017, Pp 112-120
Thomas Stiehl | Anna Marciniak-Czochra

Recent progress and open challenges in modeling p53 dynamics in single cells

Volume 3, Issue , 01 June 2017, Pp 54-59
Eric Batchelor | Alexander Loewer

Perspectives on Big Data applications of health information

Volume 3, Issue , 01 June 2017, Pp 36-42
Isaac Cano | Akos Tenyi | Emili Vela | Felip Miralles | Josep Roca

A CRISPR view of gene regulation

Volume 1, Issue , 01 February 2017, Pp 1-8
Budhaditya Banerjee | Richard I. Sherwood