The Current Opinion journals were developed out of the recognition that it is increasingly difficult for specialists to keep up to date with the expanding volume of information published in their subject. Elsevier’s Current Opinion journals comprise of 26 leading titles in life sciences and adjacent fields.

Current Opinion in Structural Biology

5-Year Impact Factor: 6.580
Issues per year: 6 issues
Editorial Board

Current Opinion in Structural Biology

Current Opinion in Structural Biology aims to stimulate scientifically grounded, interdisciplinary, multi-scale debate and exchange of ideas. It contains polished, concise and timely reviews and opinions, with particular emphasis on those articles published in the past two years. In addition to describing recent trends, the authors are encouraged to give their subjective opinion of the topics discussed.

In Current Opinion in Structural Biology we help the reader by providing in a systematic manner:

1. The views of experts on current advances in their field in a clear and readable form.
2. Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications.

Current Opinion in Structural Biology will serve as an invaluable source of information for researchers, lecturers, teachers, professionals, policy makers and students.

Division of the subject into sections

The subject of Structural Biology is divided into twelve themed sections, each of which is reviewed once a year. Each issue contains two sections, and the amount of space devoted to each section is related to its importance.

  • Folding and Binding
  • Nucleic acids and their protein complexes
  • Macromolecular Machines
  • Theory and Simulation
  • Sequences and Topology
  • New constructs and expression of proteins
  • Membranes
  • Engineering and Design
  • Carbohydrate-protein interactions and glycosylation
  • Biophysical and molecular biological methods
  • Multi-protein assemblies in signalling
  • Catalysis and Regulation

Selection of topics to be reviewed

Section Editors, who are major authorities in the field, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasised. Section Editors commission reviews from authorities on each topic that they have selected. The Editorial Board provides support to the Editors and the Section Editors with their comments and suggestions on names and topics.

Review articles in Current Opinion in Structural Biology are by invitation only. The journal does not accept manuscripts other from those invited by section editors, appointed by the main editors Tom Blundell and Keith Moffatt each year.

Review Articles

Authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous two years.

Editorial Overview

Section Editors write a short overview at the beginning of the section to introduce the reviews and to draw the reader's attention to any particularly interesting developments.

This successful format has made Current Opinion in Structural Biology one of the most highly regarded review journals in the field with an Impact factor of 9.344.

Best Cited over the last year.

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Molecular dynamics simulations of large macromolecular complexes

Volume 31, Issue , 01 April 2015, Pp 64-74
Juan R. Perilla | Boon Chong Goh | C. Keith Cassidy | Bo Liu | Rafael C. Bernardi | Till Rudack | Hang Yu | Zhe Wu | Klaus Schulten

Inhibition of protein aggregation and amyloid formation by small molecules

Volume 30, Issue , 01 February 2015, Pp 50-56
Andrew J. Doig | Philippe Derreumaux

Relating sequence encoded information to form and function of intrinsically disordered proteins

Volume 32, Issue , 01 June 2015, Pp 102-112
Rahul K. Das | Kiersten M. Ruff | Rohit V. Pappu

Allostery without a conformational change? Revisiting the paradigm

Volume 30, Issue , 01 February 2015, Pp 17-24
Ruth Nussinov | Chung Jung Tsai

Intrinsically disordered proteins: Emerging interaction specialists

Volume 35, Issue , 01 December 2015, Pp 49-59
Peter Tompa | Eva Schad | Agnes Tantos | Lajos Kalmar

Assessing and maximizing data quality in macromolecular crystallography

Volume 34, Issue , 01 October 2015, Pp 60-68
P. Andrew Karplus | Kay Diederichs

The structural biology of CRISPR-Cas systems

Volume 30, Issue , 01 February 2015, Pp 100-111
Fuguo Jiang | Jennifer A. Doudna

De novo protein design: How do we expand into the universe of possible protein structures?

Volume 33, Issue , 01 August 2015, Pp 16-26
Derek N. Woolfson | Gail J. Bartlett | Antony J. Burton | Jack W. Heal | Ai Niitsu | Andrew R. Thomson | Christopher W. Wood

Methyl-specific isotopic labeling: A molecular tool box for solution NMR studies of large proteins

Volume 32, Issue , 01 June 2015, Pp 113-122
Rime Kerfah | Michael J. Plevin | Remy Sounier | Pierre Gans | Jerome Boisbouvier

Recent insights into structures and functions of C-type lectins in the immune system

Volume 34, Issue , 01 October 2015, Pp 26-34
Kurt Drickamer | Maureen E. Taylor

Molecular interactions between chondroitin-dermatan sulfate and growth factors/receptors/matrix proteins

Volume 34, Issue , 01 October 2015, Pp 35-42
Shuji Mizumoto | Shuhei Yamada | Kazuyuki Sugahara

The β-barrel membrane protein insertase machinery from Gram-negative bacteria

Volume 31, Issue , 01 April 2015, Pp 35-42
Nicholas Noinaj | Sarah E. Rollauer | Susan K. Buchanan

Advances in free-energy-based simulations of protein folding and ligand binding

Volume 36, Issue , 01 February 2016, Pp 25-31
Alberto Perez | Joseph A. Morrone | Carlos Simmerling | Ken A. Dill

Recent advances in sortase-catalyzed ligation methodology

Volume 38, Issue , 01 June 2016, Pp 111-118
John M. Antos | Matthias C. Truttmann | Hidde L. Ploegh

The structure of fibrils from 'misfolded' proteins

Volume 30, Issue , 01 February 2015, Pp 43-49
Beat H. Meier | Anja Böckmann

How dynein and dynactin transport cargos: A structural perspective

Volume 37, Issue , 01 April 2016, Pp 62-70
Andrew P. Carter | Aristides G. Diamant | Linas Urnavicius

Structure, mechanism and cooperation of bacterial multidrug transporters

Volume 33, Issue , 01 August 2015, Pp 76-91
Dijun Du | Hendrik W. van Veen | Satoshi Murakami | Klaas M. Pos | Ben F. Luisi

MCM: One ring to rule them all

Volume 37, Issue , 01 April 2016, Pp 145-151
Tom D. Deegan | John F.X. Diffley

Pichia pastoris as an expression host for membrane protein structural biology

Volume 32, Issue , 01 June 2015, Pp 9-17
Bernadette Byrne

Structural and physico-chemical effects of disease and non-disease nsSNPs on proteins

Volume 32, Issue , 01 June 2015, Pp 18-24
Tugba G. Kucukkal | Marharyta Petukh | Lin Li | Emil Alexov

Principles of protein structural ensemble determination

Volume 42, Issue , 01 February 2017, Pp 106-116
Massimiliano Bonomi | Gabriella T. Heller | Carlo Camilloni | Michele Vendruscolo

Protein contact network topology: A natural language for allostery

Volume 31, Issue , 01 April 2015, Pp 43-48
Luisa Di Paola | Alessandro Giuliani

Camelid nanobodies: Killing two birds with one stone

Volume 32, Issue , 01 June 2015, Pp 1-8
Aline Desmyter | Silvia Spinelli | Alain Roussel | Christian Cambillau